Aim of the study: The aim of this study was to assess physical activity and quality of life in future health professionals. Respondents and materials: 108 students of the Medical School Karlovac participated in the research. Students attend 4th and 5th grade and study for the profession of nurse / general medical technician and physiotherapeutic technician. The survey questionnaire in three parts was used for the research. The first part consists of sociodemographic data (gender, age, place of residence, direction of education). The second part of the questionnaire is based on the International Physical Activity Level Questionnaire (IPAQ) which examines physical activity in the last seven days. The third part of the questionnaire is based on the Quality of Life Questionnaire for Children and Adolescents (Kidscreen 52). It consists of 52 statements that respondents rated ranging from 1 to 5. Results: Students in the field of physiotherapy technician are more physically active than students in the field of nurse / medical technician when it comes to extremely strenuous physical activity. There is also a difference in performing physical activities between students living in rural areas and students living in urban areas. Students living in rural areas are more physically active than students living in urban areas when it comes to extremely strenuous physical activity. However, when it comes to moderate physical activity, there is no difference. When it comes to assessing quality of life, there are no differences between students living in rural areas and students living in urban areas. On the other hand, it has been shown that the intensity of physical activity affects the assessment of quality of life. Conclusion: Future health professionals are mostly physically active and have a positive assessment of personal quality of life.