Puberty is one of the developmental stages of a young person in which occures many physical, hormonal and psychological changes. This period is characterized by changes in the brain and hormonal system. Therefore, young people experience physical, biological, psychological and social changes that are reflected in the change of the primarily physical appearance, all the way to the formation of self-perception and self-regulation, and the development of interpersonal relationships and social changes. Alcohol has played an important role throughout long human history. It has been widely applied from worship to pharmacological purposes with the development of medicine. It was also used as a means of entertainment and enjoyment, then and today. The culture and customs of alcohol consumption are learned at a very early age. Alcohol as such is first on the list of addictive drugs that young people resort to. Alcohol although a means of addiction to young people has become completely acceptable. It is precisely in children at puberty that a kind of conflict between mature and immature desires occurs. That is, there is a strong desire to experiment, including with alcohol. Acute or chronic health consequences can arise from the initial experimentation with alcohol. Therefore, the aim of this research was to collect data on the knowledge, experiences and opinions of students of the Undergraduate Professional Study of Nursing, full-time and part-time at the Faculty of Health Studies in Rijeka on puberty and alcoholism in puberty. Also, two hypotheses were set up from which the one that says that nursing students did not have enough knowledge about alcohol at puberty was accepted. The hypotheses were confirmed based on the responses obtained from the respondents.