Parenting is by itself a stressful task. Most parents have common expectations that their child is healthy therefore when faced with the challenge of parenting of a child with developmental difficulties is understandable to expect that it will have an impact on all aspects of their life as well as quality itself. The main objective of this study was to examine quality of life, coping with stress, and resilience components in families of children with disabilities. Subjects and methods: a group of 40 parents who have children with disabilities was examined. As a control group, 40 parents who have children with typical development were also examined. The following were questionnaires used: Socio-demographic data questionnaire, Quality of life questionnaire, Family resilience questionnaire and Cognitive emotional regulation questionnaire.. Results: The results showed that there was no difference in the age and sex of the child. Also, no statistically significant differences were found in the examination of education and marital status. The age of the parents and the number of children in both groups were not statistically significant, but a difference was found in the employment of parents where there was higher unemployment among the parents of children with disabilities. Parents of children with typical development assess their physical and mental condition better, as well as social interaction and the environment and better family resilience.. Conclusion: It can be concluded that parents of children with disabilities assess quality of life, resilience and cognitive-emotional regulation at lower point than parents of children with typical development.