We are exposed to stress on a daily basis regardless of gender, age, marital status and education. Mechanisms of coping with stress help us core with stress more easily. Anxiety depressive disorders are unfortunately increasingly recognized among the younger population or impair the quality of life and require exhaustive work and education for people. The main goal of this research is to examine the differences in the mechanisms of coping with stress in healthy individuals in relation to people who suffer from some of the anxiety disorders or depression. The following instruments were used in the research: 1. COPE - brief questionnaire, 2. DASS questionnaire, 3. Quality of life questionnaire, 4. Sociodemographic data questionnaire. The research included a total of 100 patients. Twenty-five patients hospitalized in the daily hospital for Integrative Psychiatry and twenty-five patients hospitalized in the daily hospital for non-psychotic disorders, the Psychiatric Hospital Sv. Ivan, Zagreb. The other 50 subjects are a control group, i.e. healthy individuals. The results of the research show that the level of anxiety, depression and stress are higher in subjects who are treated for any of the anxiety disorders or depression, compared to healthy subjects. In stress coping strategies, healthy subjects use a problem-oriented coping strategy, and subjects who are treated for one of the anxiety disorders or depression use an avoidance strategy. No significant difference was found in emotion-focused coping strategies between healthy subjects and subjects who are treated for one of the anxiety disorders or depression. The analysis of the data shows that the quality of life is higher in healthy subjects compared to subjects who are treated for one of the anxiety disorders or depression in areas such as mental and physical health and social relations.