INTRODUCTION: The consumption of psychoactive substances has been present since ancient times. In different cultures, leaves of different plants were consumed to achieve a certain sense of relaxation and happiness.The consumption of psychoactive substances has an impact on the psychological and physical functioning of humans. Each type of psychoactive substance results in the occurrence of characteristic symptoms after consumption. Depending on the amount of psychoactive tweezers taken, the severity of symptoms will be pronounced. OBJECTIVE: The aim is to examine the attitudes of undergraduate Professional Studies of Nursing at the Faculty of Health studies in Rijeka, on the attitudes related to the consumption of psychoactive substances. The specific objectives are to determine whether the views of nursing students on the consumption of psychoactive substances vary according to the sex, age and year of study. METHODS: The collection of data necessary for carrying out the research was carried out through an online survey questionnaire, which was developed in the Google forms platform. The questionnaire was drawn up by the author of the paper and divided into two parts. The first part of the survey collected socio-demographic data (age, gender, study programme, year of study and completed secondary education) related to the objectives set. The following questions of the questionnaire are aimed at examining student attitudes, created in the light of the hypotheses posed. Prior to the beginning of the survey survey, respondents were informed about the collection of information for the purpose of preparing the final paper. RESULTS: Students of undergraduate professional study of nursing , regular and part-time study participated in this study. The total number of respondents was 120, 61 full-time and 59 part-time students. The results of the study confirm the hypothesis 1 that the views of nursing students on the consumption of psychoactive substances do not differ according to the sex of the subjects. They also confirm hypothesis 2, that nursing students' attitudes on the consumption of psychoactive substances do not differ in terms of age and hypothesis 3, that nursing students' attitudes on the consumption of psychoactive substances do not differ with considering the year of study based on the results obtained. CONCLUSION: Students of the undergraduate Professional study of nursing believe that the consumption of psychoactive substances has serious consequences for the health and functioning of the individual, they also have negative attitudes towards the consumption of psychoactive substances and they smash that education on the harmfulness and effects of psychoactive substances is very important.