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master's thesis
USPOREDBA OTVORENE KIRURŠKE I TRANSKATETERSKE IMPLANTACIJE MITRALNOG ZALISKA U KLINIČKOM BOLNIČKOM CENTRU RIJEKA
2023. urn:nbn:hr:184:973763
Capan, Iva
University of Rijeka
Faculty of Health Studies

Cite this document

Capan, I. (2023). USPOREDBA OTVORENE KIRURŠKE I TRANSKATETERSKE IMPLANTACIJE MITRALNOG ZALISKA U KLINIČKOM BOLNIČKOM CENTRU RIJEKA (Master's thesis). Rijeka: University of Rijeka, Faculty of Health Studies. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:973763

Capan, Iva. "USPOREDBA OTVORENE KIRURŠKE I TRANSKATETERSKE IMPLANTACIJE MITRALNOG ZALISKA U KLINIČKOM BOLNIČKOM CENTRU RIJEKA." Master's thesis, University of Rijeka, Faculty of Health Studies, 2023. https://urn.nsk.hr/urn:nbn:hr:184:973763

Capan, Iva. "USPOREDBA OTVORENE KIRURŠKE I TRANSKATETERSKE IMPLANTACIJE MITRALNOG ZALISKA U KLINIČKOM BOLNIČKOM CENTRU RIJEKA." Master's thesis, University of Rijeka, Faculty of Health Studies, 2023. https://urn.nsk.hr/urn:nbn:hr:184:973763

Capan, I. (2023). 'USPOREDBA OTVORENE KIRURŠKE I TRANSKATETERSKE IMPLANTACIJE MITRALNOG ZALISKA U KLINIČKOM BOLNIČKOM CENTRU RIJEKA', Master's thesis, University of Rijeka, Faculty of Health Studies, accessed 17 November 2024, https://urn.nsk.hr/urn:nbn:hr:184:973763

Capan I. USPOREDBA OTVORENE KIRURŠKE I TRANSKATETERSKE IMPLANTACIJE MITRALNOG ZALISKA U KLINIČKOM BOLNIČKOM CENTRU RIJEKA [Master's thesis]. Rijeka: University of Rijeka, Faculty of Health Studies; 2023 [cited 2024 November 17] Available at: https://urn.nsk.hr/urn:nbn:hr:184:973763

I. Capan, "USPOREDBA OTVORENE KIRURŠKE I TRANSKATETERSKE IMPLANTACIJE MITRALNOG ZALISKA U KLINIČKOM BOLNIČKOM CENTRU RIJEKA", Master's thesis, University of Rijeka, Faculty of Health Studies, Rijeka, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:184:973763

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TitleUSPOREDBA OTVORENE KIRURŠKE I TRANSKATETERSKE IMPLANTACIJE MITRALNOG ZALISKA U KLINIČKOM BOLNIČKOM CENTRU RIJEKA
Title (english)COMPARISON OF OPEN SURGICAL AND TRANSCATHETER IMPLANTATION OF MITRAL VALVE IN CLINICAL HOSPITAL CENTRE RIJEKA
AuthorIva Capan
MentorVjekoslav Tomulić (mentor)
Committee memberTomislav Krčmar (predsjednik povjerenstva)
Committee memberTomislav Jakljević (član povjerenstva)
Committee memberZlatko Čubranić (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Health Studies
Rijeka
Defense date and country2023-12-11, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Nursing
Abstract
Bolesti mitralnog zaliska jedne su od najčešćih valvularnih grešaka, a u bolesnika mogu uzrokovati dispneju, ortopneju, poremećaje srčanog ritma ali i težu kliničku sliku poput razvoja akutnog plućnog edema. Uz medikamentozni pristup, jedina uspješna metoda liječenja je invazivni zahvat: kirurška otvorena ili perkutana (transkateterska) metoda. Cilj ovog istraživanja bio je analizirati postiže li se transkateterskom metodom liječenja bolesti mitralnog zaliska manji broj komplikacija, kraće trajanje hospitalizacije i poboljšanje kvalitete života u odnosu na bolesnike liječene kirurškom zamjenom mitralnog zaliska. Glavni uključujući kriteriji bili su: mitralna stenoza , mitralna insuficijencija, te podvrgnutost invazivnom zahvatu. Ispitanici su bili podijeljeni u dvije skupine: kirurška skupina od 13 ispitanika i perkutana skupina od 6 ispitanika. Podaci o bolesnicima su prikupljeni u bazu podataka te je učinjena komparativna analiza dviju skupina. Ispitanici u obje skupine bili su starije životne dobi. Skupina ispitanika liječena perkutano imala je viši preoperativni profil rizika. Bolesnici liječeni perkutanim pristupom imali su manji broj infekcija i krvarenja, brži oporavak, te time kraće trajanje hospitalizacije i potrebu za boravkom u jedinici intenzivnog liječenja, iako nije postignuta statistička značajnost u navedenim kategorijama. Ejekcijska frakcija lijeve klijetke značajno je poboljšana nakon transkateterske implantacije mitralnog zaliska. U obje je skupine nakon operativnog liječenja značajno je poboljšana kvaliteta života, odnosno stupanj podnošenja tjelesne aktivnosti. Hospitalni mortalitet nije evidentiran. Izbor perkutanog, transkateterskog u odnosu na otvoreno liječenje bolesti mitralne valvule smanjuje dodatan rizik povezan s kirurškim zahvatima U našem se istraživanju perkutani pristup pokazao sigurnim i učinkovitim, te u potpunosti usporedivim sa zlatnim standardom, otvorenom kirurškom metodom. Rezultati oba načina liječenja u KBC-u Rijeka usporedivi su sa onima u referentnim svjetskim centrima.
Abstract (english)
One of the most common valvular defects is mitral valvular pathology. It can cause dyspnea, orthopnea, and heart rhythm disorders, but also a more severe clinical picture such as the development of acute pulmonary oedema. Besides the medicinal approach, the only successful treatment method is an invasive procedure: open surgical or percutaneous (transcatheter). The aim of this research was to analyse whether fewer complications, shorter hospitalization time, and improved quality of life are achieved by the transcatheter method in the treatment of mitral valve disease. The main inclusion criteria were mitral stenosis, mitral insufficiency and undergoing an invasive procedure. The patients were divided into two groups: a surgical group of 13 subjects and a percutaneous group of 6 subjects. A comparative analysis of the two groups was made based on the collected database data. The subjects in both groups were elderly. The group of subjects treated percutaneously had a higher preoperative risk profile. Patients treated with a percutaneous approach had a lower number of infections and bleeding, a faster recovery, and thus a shorter duration of hospitalization and the need for a stay in the intensive care unit, although statistical significance was not achieved in the mentioned categories. Left ventricular ejection fraction was significantly improved after transcatheter mitral valve implantation. In both groups, after operative treatment, the quality of life, i.e. the level of tolerance of physical activity, improved significantly. Hospital mortality was not recorded. Choosing percutaneous, transcatheter versus open treatment of mitral valve disease reduces the additional risk associated with surgical procedures. In our research, the percutaneous approach proved safe, effective, and fully comparable to the gold standard, the open surgical method. The results of both treatment methods at KBC Rijeka are comparable to those in reference centers worldwide.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:973763
Study programmeTitle: Graduate university study of Nursing: Healthcare Management (Biomedicine and Healthcare; clinical medical sciences)
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2023-12-13
Terms of useLicence In copyright icon
Created on2023-12-03 15:18:47