prikaz prve stranice dokumenta Enhancing the bioavailability and activity of natural antioxidants with nanobubbles and nanoparticles
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Scientific paper - Review paper
Enhancing the bioavailability and activity of natural antioxidants with nanobubbles and nanoparticles
Redox Report, 29 (2024), 1; 1-15. https://doi.org/10.1080/13510002.2024.2333619
Čolić, Miroslav; Kraljević Pavelić, Sandra; Peršurić, Željka; Agaj, Andrea; Bulog, Aleksandar; Pavelić, Krešimir

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Čolić, M., Kraljević Pavelić, S., Peršurić, Ž., Agaj, A., Bulog, A. & Pavelić, K. (2024). Enhancing the bioavailability and activity of natural antioxidants with nanobubbles and nanoparticles. Redox Report, 29. (1), 1-15. doi: 10.1080/13510002.2024.2333619

Čolić, Miroslav, et al. "Enhancing the bioavailability and activity of natural antioxidants with nanobubbles and nanoparticles." Redox Report, vol. 29, no. 1, 2024, pp. 1-15. https://doi.org/10.1080/13510002.2024.2333619

Čolić, Miroslav, Sandra Kraljević Pavelić, Željka Peršurić, Andrea Agaj, Aleksandar Bulog and Krešimir Pavelić. "Enhancing the bioavailability and activity of natural antioxidants with nanobubbles and nanoparticles." Redox Report 29, no. 1 (2024): 1-15. https://doi.org/10.1080/13510002.2024.2333619

Čolić, M., et al. (2024) 'Enhancing the bioavailability and activity of natural antioxidants with nanobubbles and nanoparticles', Redox Report, 29(1), pp. 1-15. doi: 10.1080/13510002.2024.2333619

Čolić M, Kraljević Pavelić S, Peršurić Ž, Agaj A, Bulog A, Pavelić K. Enhancing the bioavailability and activity of natural antioxidants with nanobubbles and nanoparticles. Redox Report [Internet]. 2024 [cited 2024 November 10];29(1):1-15. doi: 10.1080/13510002.2024.2333619

M. Čolić, S. Kraljević Pavelić, Ž. Peršurić, A. Agaj, A. Bulog and K. Pavelić, "Enhancing the bioavailability and activity of natural antioxidants with nanobubbles and nanoparticles", Redox Report, vol. 29, no. 1, pp. 1-15, 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:347987. [Accessed: 10 November 2024]

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Metadata
Title (english)Enhancing the bioavailability and activity of natural antioxidants with nanobubbles and nanoparticles
AuthorMiroslav Čolić
AuthorSandra Kraljević Pavelić
AuthorŽeljka Peršurić
AuthorAndrea Agaj
AuthorAleksandar Bulog
AuthorKrešimir Pavelić
Author's institutionUniversity of Rijeka
Faculty of Health Studies
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Abstract (english)
Objectives: Many polyphenols such as EGCG from green tea, curcumin, apigenin, resveratrol or the alkaloid berberine show in-vitro activity that is much higher than FDA and EU approved drugs. And yet, while mice studies show excellent results, human clinical trials have so far been quite disappointing. Methods: In this review paper we accordingly present data from scientific literature and publicly available databases that support further development of nanoformulations for enhanced natural antioxidants bioavailability and activity. Results: Nanobubbles, and nanoparticles may enhance the polyphenols bioavailability and special coatings can be used to avoid liver fast inactivation. Zeolites have also been tested as carriers for bioactive compounds from the Mediterranean food. Other polyphenols can be used with nanoemulsions for synergistic antioxidants treatment. Finally, nanobubbles in the presence of ferric or copper ions at low pH as in human stomach or lysosomes can produce small amount of hydroxyl radicals, stimulating activation of Nrf2 transcription factor and detox enzymes. Discussion: A number of nanoformulations, including nanobubbles loaded with natural antioxidants may be used with low carbs and protein diet as a support to chemotherapy or treatment of advanced tumors. Good results in animal studies of neurodegenerative diseases and type II diabetes were also observed
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleRedox Report
Numberingvol. 29, no. 1, pp. 1-15
p-ISSN1351-0002
e-ISSN1743-2928
DOIhttps://doi.org/10.1080/13510002.2024.2333619
URN:NBNurn:nbn:hr:184:347987
Publication2024
ProjectNumber: N/A
Title (croatian): Znanstveni centar izvrsnosti za bioprospecting mora
Title (english): Scientific Center of Excellence for Bioprospecting of the sea
Acronym: BioProCro
Leader: Rozelinda Čož-Rakovac
Jurisdiction: Croatia
Funding stream: ZCI
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) icon
Created on2024-04-10 09:30:10