Introduction and research objectives: This study deals with the relationship between diabetes and myocardial infarction in patients admitted to the Unified Emergency Department of the Šibenik General Hospital in 2023. The aim is to investigate the prevalence of myocardial infarction in patients with diabetes, the distribution by age group, gender differences and the proportion of patients with diabetes who experience myocardial infarction and vice versa. Hypotheses include a high prevalence of myocardial infarction in patients with diabetes, the highest incidence in older age groups, a higher prevalence in men with diabetes, and a significant proportion of patients with both conditions. Materials and methods: In a study conducted at the Šibenik General Hospital, the relationship between diabetes and myocardial infarction was investigated using retrospective data collection of patients admitted for these conditions in 2023. The sample includes patients of both sexes and all age groups. The analysis is based on data from the hospital information system, including age, gender and diagnosis. SPSS was used for statistical processing, with t-test and chi-square test for hypothesis evaluation. The study was ethically approved, with emphasis on anonymity and data security. Results: The study of 407 patients at Šibenik General Hospital revealed that 57.5 % had diabetes and 65.6 % had myocardial infarction, with 23.1 % of patients having both conditions. The analysis of gender and age revealed a higher prevalence of diabetes in men and the highest number of myocardial infarctions in those over 70 years of age. Statistical analysis revealed no significant association between gender and myocardial infarction, but a significant association was found between age and the combination of diabetes and myocardial infarction, indicating an increased risk with age. Conclusion: The research at the Šibenik General Hospital confirmed the association between diabetes and myocardial infarction, with a higher prevalence of myocardial infarction in patients with diabetes, especially in older age groups. No statistically significant gender differences were found in the prevalence of heart attacks in patients with diabetes. The study emphasises the importance of prevention and risk management to reduce the frequency and severity of myocardial infarction in people with diabetes.