Introduction: ST-segment elevation myocardial infarction (STEMI) remains a major cause of premature death worldwide and, despite recent advances, controversy remains regarding its optimal management. Most STEMIs are caused by atherosclerotic plaque rupture with vessel occlusion due to secondary thrombosis, with the extent of subsequent myocardial injury depending on the area of the myocardium covered by the vessel, the duration of the occlusion, and the presence of collaterals. Therefore, expeditious establishment of patency of blood vessels is the basis of treatment of this condition. The aim of this study was to determine the frequency of STEMI as an indication for emergency medical transport to Zadar General Hospital. Materials and methods: A retrospective analysis of data from the IT system of the Department of Emergency Medicine of Zadar County was carried out, which included 821 patients treated under the diagnosis of acute myocardial infarction with ST elevation (diagnoses I20-I25 in the International Classification of Diseases), transported to the Zadar General Hospital in the period from 01.01.2014. until 31.12.2023. years. Results: This research determined that myocardial infarction with ST elevation occurs more often in men, after the age of 40, with no statistically significant difference in the groups between 40 and 60 years of age and the group over 60 years of age and in the winter months. Conclusion: STEMI is significantly present in the general population, represents a major public health problem and requires urgent medical intervention and a long-term preventive strategy to reduce the risk of mortality and improve patient health outcomes.