Larynx tumors are most common head and neck tumors with an incidence of 20 - 28%. Despite significant progress in treatment methods, consequences after surgery for laryngectomy and other treatment methods are frequent. Possible adverse effects are associated with the function of the musculoskeletal system of the head, neck, shoulder, chest and spine of the laryngectomized patient. Lack of activity negatively affects the functional dysfunction caused by timely and individually tailored physiotherapy procedures. Medical activities involved in the treatment of cancer of the larval cancer have set guidelines and criteria for the field of oncological physiotherapy whose area of work is laryngectomized patients. Techniques and methods to be used during intervention, physiotherapist choices based on physiotherapeutic evaluation and current functional status. The aim of this study was to determine whether there was a statistically significant difference between respiratory index, saturation and spirometry parameters observed between the experimental and control group at the beginning and end of the physiotherapeutic intervention. Experimental group of respondents were laryngectomized patients with special manual techniques, while the control group consisted of laryngectomized patients who conducted respiratory training. From the analysis of the results it can be concluded that the application of special manual techniques in the experimental group of respondents statistically significantly improved the observed saturation parameter. Other variables do not find a statistically significant improvement between the final measurements of the experimental and control groups although it is descriptively present in most of them. Although a statistically significant difference has also been found in the FEV1% parameter for the final measurement between the experimental and control group of respondents, this result can not be taken into account since the control group initially showed more value than the experimental. For future research we can suggest that physiotherapeutic procedures of special manual techniques and respiratory training be carried out over a period of time longer than a week, and leave room for new research. We are asking whether the outcome of physiotherapy procedures and their efficacy would have a greater chance of progress if they were to spend for a longer period of time. Due to the positive influence on physical and psychosocial function physiotherapy is of great importance in the overall rehabilitation of the larynx omission. It is necessary in the field of oncological problems due to the methods and techniques that can be applied and certainly need to have their place in a complex approach to the patient after laringectomy.