In modern society, obesity is one of the most visible but also one of the most neglected public health problems. Obesity most often leads to changes in an individual's psychic state, such as depression, anxiety, feelings of helplessness, diminished self-esteem, all of which ultimately affect an individual's mental health. Through the education of the population, it is necessary to emphasize the importance of preventing obesity. Overweight and obese people often face stigmatization that affects almost every area of their functioning (discrimination at work, social exclusion and public ridicule). Since obesity can have a significant impact on the health and thus the mental health of individuals, various studies have been conducted which in many cases have shown the negative impact of obesity on the onset of depression, a decline in self-esteem, from what I noticed the need to raise awareness about obesity in the general population of the Istrian region (County of Istria). The aim and purpose of the research is to present the impact, attitudes and perceptions of the population of the Istrian region (County of Istria) towards obesity as a disease, or just familiarity of the concept of "mental health". This study examined opinion in the general population of the Istrian region (County of Istria) about the impact of obesity on mental health and whether there are significant differences by age, gender, education and place of residence in the cities of the Istrian region (County of Istria). The final results have shown the perception of the population of Istria as a disease, the positive or negative impact of obesity on mental health, and I will try to give a clearer picture of what should be changed and in what direction nursing should be directed as a profession in preventing the development of obesity itself.