The thesis describes the implementation of the project "Aestheticization and rehumanization of hospital environment: Art for health's sake" and is dedicated to researching the effect of artistic activity on the health and mood of patients and visitors and hospital employees. The research is based on research examples from world practice that prove the beneficial effects of art on the health and mood of people living in a hospital environment. The research work was carried out by quantitative method in the form of anonymous survey questionnaires at the children's wards of six Deparments of KBC Zagreb and at the Children's Hospita Zagreb from March 2018 to June 2019. Ten hospital spaces intended for the treatment of children from infancy to adolescence were painted. The questionnaire surveyed parents, school children and employees before and after the art intervention. The collected samples of completed questionnaires were processed by the statistical method of calculating average and relative values and descriptive analysis. The questionnaire covered 40.48% of employees before and 52.83% after painting, while the rest are visitors (parents) 30.95% before, ie 35.84% after painting, and patients (children and mothers) 30.95%, ie 11.31% after painting. It should be emphasized that this is a convenient sample of respondents who found themselves in a particular department at a particular time. Regarding the result of the research, it is important to point out that 90% of respondents supported this project, agreed with the statement that art interventions have a positive effect on the feeling of comfort in the hospital space and in the same percentage believes that the interior design of the hospital space is important. Hospital intervention is a good idea. This project, which, in addition to painting, presented the affirmative results of the research, contributed to increasing awareness of the importance of art in the planning of hospital space. The space enriched by artistic interventions achieves an aesthetic and therapeutic effect on the health of children and the entire hospital community. At the same time, it involves young artists in socially engaged projects and moves the Croatian art scene beyond the framework of cultural institutions, creating new spaces for interdisciplinary cooperation of the scientific community.