INTRODUCTION - Menopause is a natural biological process during the reproductive life of women that most often occurs between the ages of 41 and 58. The symptoms of menopause are diverse, and the most common are cycle changes, night sweats, sleep disturbances and other. Physical activity is recommended to reduce symptoms in postmenopausal women. Therefore, the aim of this research is to investigate the connection between physical activity and the mental health of women during postmenopausal stage. METHODS - Fifty-five participants aged 60 to 70 years participated in this study. The participants were divided into two groups: the group of physically active (N = 38) and physically inactive women (N = 17). All participants completed a questionnaire on physical activity and menopausal symptoms. RESULTS – The results of the study showed statistically significant differences in the feeling of fatigue and exhaustion between the two examined groups (p = 0.0332). Moreover, a statistically significant difference between the investigated groups was observed on the question "Do you consider yourself a happy person?" (P = 0.0239). For the questions on the assessment of mental and physical health, sleep disorders, difficulty concentrating and memory and the assessment of socialization, no statistically significant difference was found between the two investigated groups (p> 0.05). DISCUSSION – The research showed a positive effect of physical activity on the feeling of fatigue and exhaustion in the group of physically active participants, and that physically active women are considered happier people than physically inactive women, which is in accordance with available research. However, physical activity had no effect on sleep difficulties, socialization, and memory difficulties between the two investigated groups. CONCLUSION - Physical activity leads to a reduction of fatigue, exhaustion, restlessness and tension in the group of physically active women. Moreover, physically active women showed greater self-satisfaction compared to the group of physically inactive women.