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undergraduate thesis
SUVREMENO LIJEČENJE TROSTRUKO NEGATIVNOG RANOG RAKA DOJKE
2021. urn:nbn:hr:184:096832
Varaklić, Lea
University of Rijeka
Faculty of Health Studies
Department of Laboratory and Radiological Diagnostics

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Varaklić, L. (2021). SUVREMENO LIJEČENJE TROSTRUKO NEGATIVNOG RANOG RAKA DOJKE (Undergraduate thesis). Rijeka: University of Rijeka, Faculty of Health Studies. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:096832

Varaklić, Lea. "SUVREMENO LIJEČENJE TROSTRUKO NEGATIVNOG RANOG RAKA DOJKE." Undergraduate thesis, University of Rijeka, Faculty of Health Studies, 2021. https://urn.nsk.hr/urn:nbn:hr:184:096832

Varaklić, Lea. "SUVREMENO LIJEČENJE TROSTRUKO NEGATIVNOG RANOG RAKA DOJKE." Undergraduate thesis, University of Rijeka, Faculty of Health Studies, 2021. https://urn.nsk.hr/urn:nbn:hr:184:096832

Varaklić, L. (2021). 'SUVREMENO LIJEČENJE TROSTRUKO NEGATIVNOG RANOG RAKA DOJKE', Undergraduate thesis, University of Rijeka, Faculty of Health Studies, accessed 06 April 2025, https://urn.nsk.hr/urn:nbn:hr:184:096832

Varaklić L. SUVREMENO LIJEČENJE TROSTRUKO NEGATIVNOG RANOG RAKA DOJKE [Undergraduate thesis]. Rijeka: University of Rijeka, Faculty of Health Studies; 2021 [cited 2025 April 06] Available at: https://urn.nsk.hr/urn:nbn:hr:184:096832

L. Varaklić, "SUVREMENO LIJEČENJE TROSTRUKO NEGATIVNOG RANOG RAKA DOJKE", Undergraduate thesis, University of Rijeka, Faculty of Health Studies, Rijeka, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:184:096832

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Metadata
TitleSUVREMENO LIJEČENJE TROSTRUKO NEGATIVNOG RANOG RAKA DOJKE
Title (english)CONTEMPORARY TREATMENT OF TRIPLE-NEGATIVE EARLY-STAGE BREAST CANCER
AuthorLea Varaklić
MentorIngrid Belac-Lovasić (mentor)
Committee memberInes Mrakovčić-Šutić (predsjednik povjerenstva)
Committee memberDuška Petranović (član povjerenstva)
Committee memberIngrid Belac-Lovasić (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Health Studies
(Department of Laboratory and Radiological Diagnostics)
Rijeka
Defense date and country2021-07-21, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Radiotherapy and Oncology
Abstract
Već desetljećima se provode brojna istraživanja, analize i ispitivanja u svrhu pronalaska lijeka i odgovarajuće terapije za rak. Rak predstavlja jedan od globalnih problema u javnom zdravstvu zbog visoke incidencije i mortaliteta. Od svih vrsta karcinoma, izdvaja se rak dojke čija je stopa učestalosti u porastu. Rak dojke vodeći je uzrok smrti u žena te je drugi po učestalosti u svijetu. Može se pojaviti i u muškoga spola, no statistike su pokazale da na svakog muškarca prosječno oboli sto... More žena. Trostruko negativni rak dojke jedan je od mnogih podtipova raka dojke. Naziv „trostruko negativan“ potječe od činjenice da je negativan na estrogenske receptore, progesteronske receptore te HER2 receptore. Specifičnog je fenotipa sa izuzetno lošim ishodom liječenja i terapijskim odgovorom. Češće se pojavljuje u žena mlađih od 40 godina te je veoma agresivne prirode. Pri postavljanju dijagnoze, bolest je većinski u uznapredovalom stadiju, a česta je i pojava povrata bolesti u petogodišnjem razdoblju. Trostruko negativan rak dojke zbog svojih je karakteristika teško izlječiva bolest. Trenutačno se liječi standardnom citotoksičnom kemoterapijom, dok su imunoterapija i ciljana terapija još uvijek predmet istraživanja. Less
Abstract (english)
Numerous studies, analyses and trials have been conducted for decades to find a cure and appropriate treatment for cancer. Cancer is one of the global problems in public health due to its high incidence and mortality rate. Of all types of cancer, breast cancer stands out, due to its increased rate of frequency. Breast cancer is the leading cause of death in women and is the second most common cancer worldwide. It can also occur in the male sex, but statistics have shown that the ratio of... More occurance between male and female sex is 1:100. Triple negative breast cancer is one of the many subtypes of breast cancer. The name "triple negative" comes from the fact that it lacks estrogen receptors, progesterone receptors and HER2 receptors. It has a specific phenotype with an extremely poor treatment outcome and therapeutic response. It occurs more often in women under the age of 40 and is very aggressive in nature. When making a diagnosis, the disease is often at an advanced stage, and the occurrence of disease recovery in the five-year period is common. Triple negative breast cancer is a complicated disease to treat, due to its characteristics. It is currently being treated with standard cytotoxic chemotherapy, while immunotherapy and targeted therapy are still the subject of research. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:096832
Study programmeTitle: Radiological Technology
Study programme type: professional
Study level: undergraduate
Academic / professional title: stručni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) radiološke tehnologije (stručni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) radiološke tehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-09-27 12:08:03
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