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Nuspojave oralnih antikoagulantnih lijekova
Medicina Fluminensis : Medicina Fluminensis, 51 (2015), 2; 267-275. urn:nbn:hr:184:374506
Starčević, Alma; Vukelić-Damijani, Nada; Balen, Sanja; Vlahović-Palčevski, Vera

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Starčević, A., Vukelić Damijani, N., Balen, S. & Vlahović Palčevski, V. (2015). Nuspojave oralnih antikoagulantnih lijekova. Medicina Fluminensis : Medicina Fluminensis, 51. (2), 267-275. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:374506

Starčević, Alma, et al. "Nuspojave oralnih antikoagulantnih lijekova." Medicina Fluminensis : Medicina Fluminensis, vol. 51, no. 2, 2015, pp. 267-275. https://urn.nsk.hr/urn:nbn:hr:184:374506

Starčević, Alma, Nada Vukelić Damijani, Sanja Balen and Vera Vlahović Palčevski. "Nuspojave oralnih antikoagulantnih lijekova." Medicina Fluminensis : Medicina Fluminensis 51, no. 2 (2015): 267-275. https://urn.nsk.hr/urn:nbn:hr:184:374506

Starčević, A., et al. (2015) 'Nuspojave oralnih antikoagulantnih lijekova', Medicina Fluminensis : Medicina Fluminensis, 51(2), pp. 267-275. Available at: https://urn.nsk.hr/urn:nbn:hr:184:374506 (Accessed 12 January 2025)

Starčević A, Vukelić Damijani N, Balen S, Vlahović Palčevski V. Nuspojave oralnih antikoagulantnih lijekova. Medicina Fluminensis : Medicina Fluminensis [Internet]. 2015 [cited 2025 January 12];51(2):267-275. Available at: https://urn.nsk.hr/urn:nbn:hr:184:374506

A. Starčević, N. Vukelić Damijani, S. Balen and V. Vlahović Palčevski, "Nuspojave oralnih antikoagulantnih lijekova", Medicina Fluminensis : Medicina Fluminensis, vol. 51, no. 2, pp. 267-275, 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:374506. [Accessed: 12 January 2025]

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Metadata
Title (croatian)Nuspojave oralnih antikoagulantnih lijekova
Title (english)The side effects of new oral anticoagulants
AuthorAlma Starčević
AuthorNada Vukelić-Damijani
AuthorSanja Balen
AuthorVera Vlahović-Palčevski
Author's institutionUniversity of Rijeka
Faculty of Health Studies
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Abstract (croatian)
Novi oralni antikoagulansi, izravni inhibitor trombina (dabigatran eteksilat) i inhibitori faktora Xa (rivaroksaban i apiksaban) pokazali su se jednakovrijedni ili superiorni u odnosu na varfarin u prevenciji ili liječenju venske tromboembolije. Ovaj kratki pregled opisuje mehanizam djelovanja, kliničku primjenu i nuspojave novih oralnih antikoagulansa. Kao i svi antikoagulansi, novi oralni antikoagulansi imaju povećan rizik za nastanak krvarenja. Za razli- ku od varfarina, novi oralni antikoagulansi predstavljaju klinički izazov zbog nedostatka speci- fičnog antidota i testova za mjerenje razine lijeka. Prilikom odabira antikoagulantne terapije liječnik mora primijeniti personalizirani pristup prema svakom pacijentu.
Abstract (english)
New oral anticoagulants (NOACs), direct thrombin inhibitor (dabigatran etexilat) and factor Xa inhibitors (rivaroxaban and apixaban) both show noninferiority or even superiority to warfarin in the prevention or treatment of venous thromboembolism. This brief review describes the mechanism of action, clinical use and side effects of new oral anticoagulants. Like all other anticoagulant drugs, the NOACs carry an increased risk of bleeding. Unlike warfarin, the NOACs represent a clinical challenge due to the lack of specific antidotes and tests for the measurement of drug levels. When choosing anticoagulant therapy, the physician must apply a personalized approach to each patient.
Keywords (croatian)
Keywords (english)
Languagecroatian
Languageenglish
Publication typeOther - Review
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis : Medicina Fluminensis
Numberingvol. 51, no. 2, pp. 267-275
p-ISSN1847-6864
e-ISSN1848-820X
URN:NBNurn:nbn:hr:184:374506
Publication2015
Document URLhttps://hrcak.srce.hr/139472
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-04-06 12:34:39