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master's thesis
POTPUNA PARENTERALNA PREHRANA U DJECE S MALIGNIM BOLESTIMA LIJEČENE U KLINICI ZA PEDIJATRIJU KLINIČKOG BOLNIČKOG CENTRA RIJEKA
2020. urn:nbn:hr:184:245976
Matejčić, Marijan
University of Rijeka
Faculty of Health Studies
Department of Clinical Sciences 1

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Matejčić, M. (2020). POTPUNA PARENTERALNA PREHRANA U DJECE S MALIGNIM BOLESTIMA LIJEČENE U KLINICI ZA PEDIJATRIJU KLINIČKOG BOLNIČKOG CENTRA RIJEKA (Master's thesis). Rijeka: University of Rijeka, Faculty of Health Studies. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:245976

Matejčić, Marijan. "POTPUNA PARENTERALNA PREHRANA U DJECE S MALIGNIM BOLESTIMA LIJEČENE U KLINICI ZA PEDIJATRIJU KLINIČKOG BOLNIČKOG CENTRA RIJEKA." Master's thesis, University of Rijeka, Faculty of Health Studies, 2020. https://urn.nsk.hr/urn:nbn:hr:184:245976

Matejčić, Marijan. "POTPUNA PARENTERALNA PREHRANA U DJECE S MALIGNIM BOLESTIMA LIJEČENE U KLINICI ZA PEDIJATRIJU KLINIČKOG BOLNIČKOG CENTRA RIJEKA." Master's thesis, University of Rijeka, Faculty of Health Studies, 2020. https://urn.nsk.hr/urn:nbn:hr:184:245976

Matejčić, M. (2020). 'POTPUNA PARENTERALNA PREHRANA U DJECE S MALIGNIM BOLESTIMA LIJEČENE U KLINICI ZA PEDIJATRIJU KLINIČKOG BOLNIČKOG CENTRA RIJEKA', Master's thesis, University of Rijeka, Faculty of Health Studies, accessed 23 December 2024, https://urn.nsk.hr/urn:nbn:hr:184:245976

Matejčić M. POTPUNA PARENTERALNA PREHRANA U DJECE S MALIGNIM BOLESTIMA LIJEČENE U KLINICI ZA PEDIJATRIJU KLINIČKOG BOLNIČKOG CENTRA RIJEKA [Master's thesis]. Rijeka: University of Rijeka, Faculty of Health Studies; 2020 [cited 2024 December 23] Available at: https://urn.nsk.hr/urn:nbn:hr:184:245976

M. Matejčić, "POTPUNA PARENTERALNA PREHRANA U DJECE S MALIGNIM BOLESTIMA LIJEČENE U KLINICI ZA PEDIJATRIJU KLINIČKOG BOLNIČKOG CENTRA RIJEKA", Master's thesis, University of Rijeka, Faculty of Health Studies, Rijeka, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:184:245976

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TitlePOTPUNA PARENTERALNA PREHRANA U DJECE S MALIGNIM BOLESTIMA LIJEČENE U KLINICI ZA PEDIJATRIJU KLINIČKOG BOLNIČKOG CENTRA RIJEKA
Title (english)COMPLETE PARENTERAL NUTRITION IN CHILDREN WITH MALIGNANT DISEASES TREATED IN THE PEDIATRIC CLINIC OF THE CLINICAL HOSPITAL CENTER RIJEKA
AuthorMarijan Matejčić
MentorJelena Roganović (mentor)
Committee memberGoran Palčevski (predsjednik povjerenstva)
Committee memberKristina Lah Tomulić (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Health Studies
(Department of Clinical Sciences 1)
Rijeka
Defense date and country2020-09, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Oncology
Abstract
Prehrana je važna komponenta potporne terapije u djece s malignim bolestima. Proteinsko energetska malnutricija udružena je sa slabijim podnošenjem antitumorske terapije, smanjenom imunološkom otpornosti, mijelosupresijom, duljom hospitalizacijom i lošijim ishodom liječenja. Parenteralna prehrana je indicirana u stanjima u kojima oralna i enteralna potpora ne zadovoljava nutritivne potrebe organizma. Cilj rada je prikazati institucionalna iskustva u primjeni parenteralne prehrane u djece i adolescenata s malignim bolestima koji su u razdoblju od 1. lipnja 2013. do 1. lipnja 2018. godine liječeni na Zavodu za hematologiju, onkologiju i kliničku genetiku Klinike za pedijatriju Kliničkog bolničkog centra Rijeka. Potpuna parenteralna prehrana (PPP) je provedena u 41 pacijenta (23 dječaka i 18 djevojčica), s ukupno 99 primjena (2,4 primjene po pacijentu). Prosječna dob ispitanika je iznosila 8,4 ±5,6 godina. Najčešće indikacije za primjenu PPP su bile gubitak tjelesne mase, oralni mukozitis, paralitički ileus i nemogućnost peroralnog unosa. U svih ispitanika PPP je primijenjena putem centralnog venskog katetera. Prosječno trajanje PPP iznosilo je 7,1 ± 4,8 dana. U ispitanika je zabilježen statistički značajan porast tjelesne mase. Komplikacije su zamijećene u 3% primjena (porast transaminaza i hipertrigliceridemija). PPP je učinkovita metoda nutritivne potpore pedijatrijskih onkoloških bolesnika. Komplikacije su vrlo rijetke i blage.
Abstract (english)
Nutrition is an important component of supportive therapy in children with cancer. Protein-energy malnutrition is associated with lower tolerance to antineoplastic treatment, decreased immune resistance, myelosuppression, prolonged hospitalization, and poorer treatment outcome. Parenteral nutrition is indicated in conditions in which oral and enteral support does not meet the nutritional needs of the body. The aim of this study is to present institutional experiences in the parenteral nutrition in children and adolescents with malignant diseases who were treated at the Division of Hematology, Oncology and Clinical Genetics, Department of Pediatrics, Clinical Hospital Center Rijeka, in the period from June 1st 2013 to June 1st 2018. Total parenteral nutrition (TPN) was performed in 41 patients (23 boys and 18 girls), with a total of 99 applications (2.4 applications per patient). The mean age of the subjects was 8.4 ± 5.6 years. The most common indications for TPN were weight loss, oral mucositis, paralytic ileus, and inability to oral intake. In all subjects, central venous catheters were used to administer TPN. The average duration of TPN was 7.1 ± 4.8 days. A statistically significant increase in body weight was recorded in the study. Complications were present in 3% of applications (elevated transaminase levels and hypertriglyceridemia). TPN is an effective method of nutritional support for pediatric oncology patients. Complications are very rare and mild.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:245976
Study programmeTitle: Graduate university Study of Clinical Nutrition
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra kliničkog nutricionizma (magistar/magistra kliničkog nutricionizma)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-11-09 10:31:54