The aim of this study was to examine the increase and trend of cesarean sections in the Clinical Hospital Center (CHC) Split in the period from 2016 to 2020, and to compare the data with those in the city of Zagreb, Rijeka and Osijek. Accordingly, the subject of the study was to investigate the frequency of cesarean delivery with regard to pathology during pregnancy, maternal age, number of maternal births and previous endings of labor. For the purposes of this research, data were collected in the birth books of CHC Split where data on the total number of 5993 mothers who gave birth by caesarean section were revealed, including data on the health status of mothers and newborns that led to cesarean section. Among the respondents, it was found that mothers older than 35 years more often end their pregnancies by caesarean section compared to younger pregnant women (62%). Pathologies in cesarean delivery are present in 474 mothers (7.91%). The most common pathology is gestational diabetes mellitus (31.86%), the second most common is preeclampsia which is present in 137 women with pathology (28.90%). The third most common pathology is hypothyroidism, which is present in 63 mothers with pathology (13.29%). Pathology in the form of thrombophilia was found in 42 mothers with pathology (8.86%). Given the above, pregnant women with the present pathology more often completed the delivery by caesarean section. The research included four croatian cities, Split, Zagreb, Rijeka and Osijek. In all four observed cities from 2016 to 2020, there is a higher number of natural births compared to cesarean section. According to the prevalence of caesarean section, it can be determined that it is most prevalent at birth in the city of Zagreb (32-33%). It is also evident that in all four cities the number of births is decreasing every year. If we take into account the analyzed period in terms of frequency and trends of cesarean section from 2016-2020 in CHC Split, we can conclude that there is a trend of increasing cesarean section. Starting in 2016 where the percentage of cesarean section was 26%, then in 2017 27%, in 2018 26%, in 2019 29% and in 2020 31%. In the researched period, the largest number of mothers (55.6%) had their first childbirth. Compared to the mothers who already gave birth, mothers with first pregancy are more likely to have caserean section. Pregnant women who have previously given birth by caesarean section are more likely to have a repeated caesarean section (43.6%). The danger of uterine rupture, the wishes of the pregnant woman and the obstetrician usually contribute to this. It is important to work on educating mothers during the first examinations in pregnancy, where primary health care should explain the risks and long-term consequences of cesarean section and point out the importance of vaginal delivery, which is better for mother and child, if there is no pathology.