The study was conducted on a sample of 100 respondents (healthcare and non-healthcare workers) from the University Psychiatric Hospital Sveti Ivan, Zagreb. In this study we tried to examine the correlation between the frequency of entering into conflict and different ways of reacting in a conflict situation and afterwards, and the experience of stress and quality of life. The questionnaires used for the purpose of the study were: the questionnaire of sociodemographic characteristics of the respondents, the questionnaire about conflicts on the workplace constructed specifically for the needs of the research itself, the Depression, Anxiety and Stress Assessment Scale (DASS-21), and the World Health Organization Quality of Life satisfaction rating Scale (WHOQoL-BREF). The study employed various statistical (parametric and non - parametric) methods to examine the correlation between the frequency of entering into conflicts and different ways of reacting in conflict and afterwards, and the experience of stress and satisfaction with the quality of life. The study did not confirm a positive correlation between the frequency of conflict and perceived stress, or a negative correlation between the frequency of conflict and satisfaction with the quality of life. However, it partially confirmed a correlation between the way of reacting during and after the conflict and the perceived stress and satisfaction with the quality of life.