Diseases of the heart and blood vessels are one of the main causes of mortality in the world, including in the Republic of Croatia. According to data from the World Health Organization, about 18 million people die annually from heart ischemia. During the illness, psychological, social and cultural needs disturb the patient's balance and affect his ability to perform daily activities. Holistic care, by addressing the physical, emotional, social and spiritual needs of the patient, restores balance and enables the patient to cope with his illnesses, and at the same time improve the quality of treatment. Holistic nursing is based on nursing knowledge, theories, research, intuition and creativity. The goals of this work are to show the significance of the holistic approach of nurses/technicians in health care for patients with myocardial infarction, the application of treatment in a holistic approach will be presented and standardized nursing procedures will be compared with treatments and methods of holistic approach for patients with heart attack myocardium. The methodological approach is to search electronic databases by entering key words: myocardial infarction, characteristics of a holistic approach in nursing care, quality of health care provision, standardized nursing procedures, patient satisfaction with holistic procedures. Holistic nursing moves away from separate protocols in medicine and instead encourages individualized care. Holistic care includes a wide range of approaches, including medication, education, communication, self-help and complementary medicine. In holistic nursing, all aspects of the patient and their effects on the treatment process are considered, and the patient's thoughts, emotions, cultures, opinions and attitudes are considered as contributing to recovery, happiness and satisfaction. The aim of providing holistic care is the individual assessment of the patient, the collection of information about him, the joint creation of a health care plan, implementation and positive evaluation.