INTRODUCTION: According to data from the World Health Organization, 58% of the world's population spends one-third of their lifetime at work. The workplace is an important segment of a person's life. Inadequate working conditions, high levels of workload, insufficient income, and poor interpersonal relations in the workplace are sources of stress that lead to impairment of physical and mental health and burnout syndrome in people. OBJECTIVE: The main aim of the research is to determine to what extent professional stress affects the quality of life of nurses/technicians. METHODS: The research method includes a questionnaire created based on the standardized questionnaire of scientist Grubišić-Ilić (2009) in studying stress in the medical profession. RESULTS: 100 respondents participated in the research. For the salary category, the stress frequency was determined almost daily (49.5%). The frequency was determined for the "on-call" category - every day (43%). For the category "24-hour responsibility", the frequency of stress was determined almost every day (41.2%). The frequency of overcapacity with work was determined nearly every day (42.4%). 76% of the respondents believe that the salary increase measures stress relief, the joint division of work (57%), and mutual agreements (54%). Regarding the incidence of long-term illnesses among nurses/technicians, the respondents singled out oncological disorders, endocrinological disorders, neurological disorders, pulmonary disorders, and cardiovascular disorders as a result of stress. It was found that relatively older respondents, females, rate overcapacity at work more and lack of time to deal with patients less. The most frequent stressors are communication with sick children, commu nication with incurable patients, disruptions to family life, and work with other colleagues. It was found that female respondents who belong to the age group of 21-40 years of age rate the frequency of overcapacity with work and lack of time to deal with patients the most. several times a month. CONCLUSION: Although all professions are exposed to professional stress, the profession of nurse/technician, due to its nature, is exposed to a high level of stress. A high level of stress in the work of nurses contributes to their health problems, the tendency to leave work, professional burnout, and reduced work efficiency, which results in financial losses for the work organization and a lower quality of patient care.