Insemination is process of merging male and female sexual cell. Due to impact of living conditions of younger people, desire to have a baby diminished and then reproduction is postponed, which led to infertility. Infertility is absence of pregnancy after one year of regular unprotected sexual intercourse. Main factors of infertility are age and postponing birth, fatness, smoking cigarettes, alcohol, ecological factors, diseases of reproduction system, STDs etc. To discover cause of infertility, both partners have to go through anamnesis, clinical examinations and diagnostic. Medical assisted fertilization is biomedical procedure which heals proved infertility one or both partners. There’s different methods of treating infertility. Through this seminar intrauterine insemination, in vitro fertilization, intracytoplasmic sperm injection, and dehydrated embryo transfer will be described. Along these methods often is used combination of medicaments before and during procedure of assisted fertilization, and that is called ovulation stimulation. It can led to multiple pregnancy, allergic reactions and ovarian hyperstimulation syndrome. Communication between mid-wife and patient is very important because it is one step towards healing infertility. Every procedure, medicine and protocol must be explained and deliver written to patient and her partner. Our professional help and their will to solve that specific problem can help us in further proceedings.