Breast cancer is the second most frequent malignant disease in humans, while in women the most common. It makes almost 25% of tumors in women and causes about 15% of deaths of cancer. However, in the last decade, mortality from breast cancer has started to decrease. The reasons for this lie in early detection of disease and more effective treatment. It has been shown by an effective method of organizing breast cancer search, especially in high risk groups of women. Breast cancer can be detected by various diagnostic methods at an early stage, far before the palpable formation occurs. This possibility of early diagnosis later provides better treatment outcomes. Today, with all the cognitions and medical achievements of the last decades, it is necessary to include a multidisciplinary team in the diagnosis and treatment of breast cancer and provide individual access to each patient. The combination of adjuvant radiotherapy, systemic and surgical treatment ensures maximum efficacy and the best results. Breast- conserving surgery with adjuvant radiotherapy as a method shows particularly good results with minimized side effects after surgery, so it is the method of choice before of the radical intervention. The type, order and therapeutic choice is strictly individualized, assessed according to the patient's physical condition and the degree of development of the disease.