Bladder cancer is the most common malignant disease of the urinary system. In the treatment of invasive urinary bladder cancer, creation of urostomy is most often needed. The aim of this thesis was evaluation of patients which, due to bladder cancer, had to undergo radical cystectomy and urostomy was made for urine derivation. This thesis retrospectively analyses patients with urostomy treated at the Department of Urology Clinical Hospital Center Rijeka in the period between January 1st 2014 to December 31st 2016. Data were obtained from medical files and the IBIS system of the Clinical Hospital Center Rijeka. During the observed period radical cystectomy was performed in 91 patient, and for 79 of them (86,8 %) urostomy was a method of urine derivation. Most patients were male (75 %) with the average age of 70.1 years. The Bricker method was used in 44 (55.7 %) of patients, and ureterocutaneostomy in 35 (44.3 %) patients. Stenosis of urostomy was developed in 9 (11.3%) patients, which was solved by placement of ureteral endoprothesis or by percutaneous nephrostomy. With regard to our patients, the urostomy has proven to be a satisfactory form of urine derivation due to relatively small number of complications. Since urostomy is created during a demanding and often mutilating surgery, it is very important to educate and prepare patients, which begins even before the surgery. A nurse is of great importance in the patient preparation and education.