AIM OF THE RESEARCH: The research presented in this paper examines Croatian nurses’ knowledge and attitudes about postpartum depression (PPD). To assess if nurses have sufficient knowledge level on postpartum depression and to examine the connection of knowledge and attitudes with the level of education and length of work experience. MATERIALS AND METHODS: 165 participants filled out the questionnaire via a link on various social networks. The sample is convenient. RESULTS: 90.3% of the respondents showed a sufficient level of knowledge because they achieved 60% or more correct answers on the knowledge questionnaire (χ2=63,8794, df=1, χ2gr =3,843, p<0,05). No positive association was found between a longer length of work experience and a higher level of knowledge about PPD (V∈=0,0422, p<0,05). There was also no positive association between a higher level of education and a higher level of knowledge about PPD (V∈=0,046, p<0,05). A statistically significant relationship was found between longer length of service and more positive attitudes about PPD (V∈= -0.158, p<0.05). No statistically significant association was found between a higher level of education and more positive attitudes about PPD (V∈=0.053, p<0.05). CONCLUSION: Participants showed a sufficient level of knowledge and positive attitudes about postpartum depression. However, no correlation was found between the level of knowledge, level of education and length of service. There was also no influence of the level of education on the respondents' attitudes, but longer length of service was associated with more positive attitudes towards postpartum depression