Healthcare workers are often exposed to work-related stress. Current Covid-19 pandemics has made their work even more demanding and these professionals are now considered to be even more affected by stress. Long term exposure to stress can lead to severe physical and mental illnesses. The aim of this study was to analyse stress among Institute of emergency medicine of Primorje-Gorski Kotar County employees in order to detect risk groups that are most exposed to stress as also detect stress risk factors. Finally, the survey results were used to propose preventive measures to reduce stress at work. The study included 113 employees of the Institute of emergency medicine of Primorje-Gorski Kotar County of all branch offices except the branch office in Rab. Both men and women were represented in the study almost equally, as also married and unmarried individuals. Most of the participants have had more than 5 years of work experience (72%). Results of the survey confirm that the Institute of emergency medicine of Primorje-Gorski Kotar County employees are exposed to a medium level of stress at their workplace. Medical professionals who work immediately with patients experience higher level of stress, in comparison to employees of other professions that are not included into an immediate patient care. Results emphasise work control, adequate acquaintance with work changes and work demands as risk factors for higher stress perception. On the other hand, higher age group, better interpersonal relationships and problem focused coping as a dominant way of coping with stress act as protective factors for occupational stress experience. Therefore, the results implicate that more appropriate work control (less stressful), more appropriate way of informing workers about work changes and improvement in the field of interpersonal relationships are necessary to prevent and reduce work-related stress among the employees of the Institute of emergency medicine of Primorje-Gorski Kotar County.