prikaz prve stranice dokumenta Angiogenesis and osteopontin expression in paraskeletal myeloma with plasmablastic morphology and aggressive clinical course: a report of two cases
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Angiogenesis and osteopontin expression in paraskeletal myeloma with plasmablastic morphology and aggressive clinical course: a report of two cases
Journal of Cancer Metastasis and Treatment, 8 (2022); 4783. https://doi.org/10.20517/2394-4722.2021.208
Valković, Toni; Damić, Marija Stanić; Valković, Frane; Jonjić, Nives

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Valković, T., Damić, M. S., Valković, F. i Jonjić, N. (2022). Angiogenesis and osteopontin expression in paraskeletal myeloma with plasmablastic morphology and aggressive clinical course: a report of two cases. Journal of Cancer Metastasis and Treatment, 8., 16. doi: 10.20517/2394-4722.2021.208

Valković, Toni, et al. "Angiogenesis and osteopontin expression in paraskeletal myeloma with plasmablastic morphology and aggressive clinical course: a report of two cases." Journal of Cancer Metastasis and Treatment, vol. 8, 2022, str. 16. https://doi.org/10.20517/2394-4722.2021.208

Valković, Toni, Marija Stanić Damić, Frane Valković i Nives Jonjić. "Angiogenesis and osteopontin expression in paraskeletal myeloma with plasmablastic morphology and aggressive clinical course: a report of two cases." Journal of Cancer Metastasis and Treatment 8 (2022): 16. https://doi.org/10.20517/2394-4722.2021.208

Valković, T., et al. (2022) 'Angiogenesis and osteopontin expression in paraskeletal myeloma with plasmablastic morphology and aggressive clinical course: a report of two cases', Journal of Cancer Metastasis and Treatment, 8, str. 16. doi: 10.20517/2394-4722.2021.208

Valković T, Damić MS, Valković F, Jonjić N. Angiogenesis and osteopontin expression in paraskeletal myeloma with plasmablastic morphology and aggressive clinical course: a report of two cases. Journal of Cancer Metastasis and Treatment [Internet]. 2022. [pristupljeno 23.12.2024.];8:16. doi: 10.20517/2394-4722.2021.208

T. Valković, M. S. Damić, F. Valković i N. Jonjić, "Angiogenesis and osteopontin expression in paraskeletal myeloma with plasmablastic morphology and aggressive clinical course: a report of two cases", Journal of Cancer Metastasis and Treatment, vol. 8, str. 16, 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:103873. [Citirano: 23.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:103873
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Podaci o radu
Naslov (engleski)Angiogenesis and osteopontin expression in paraskeletal myeloma with plasmablastic morphology and aggressive clinical course: a report of two cases
AutorToni Valković
AutorMarija Stanić Damić
AutorFrane Valković
AutorNives Jonjić
Autorova ustanovaSveučilište u Rijeci
Fakultet zdravstvenih studija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Extramedullary disease (EMD) of multiple myeloma (MM) can present as paraskeletal (paraosseous) plasmocytoma (PP) that arise from skeletal focal lesions or extramedullary plasmacytomas (EMP) that derive from hematogenous spread. The pathogenetic mechanisms that distinguish classical MM, PP, and EMP are still insufficiently known, as are the therapies that would be effective in EMD. The aim of this study was to evaluate immunohistochemically the angiogenesis, determined as microvessel density (MVD) and osteopontin expression in PP, of two patients with MM of plasmablastic morphology and an aggressive course of disease. We found high levels of MVD and osteopontin expression in both cases of PP. The role of angiogenesis and osteopontin in EMD should be clarified in future investigations, especially since there are no satisfactory therapeutic protocols for this form of multiple myeloma, and both of these biological factors can be the potential targets of new therapies.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prikaz slučaja
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Cancer Metastasis and Treatment
Brojčani podacivol. 8, str. 16, 4783
e-ISSN2454-2857
DOIhttps://doi.org/10.20517/2394-4722.2021.208
URN:NBNurn:nbn:hr:184:103873
Datum objave publikacije2022
URL dokumentahttps://jcmtjournal.com/article/view/4783
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Bez prerada 4.0 međunarodna (CC BY-ND 4.0)
Datum i vrijeme pohrane2024-01-15 13:26:59